Parp Inhibitor Side Effects

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them.

Parp inhibitor side effects.

Parp inhibitor associated gi toxicity. What are side effects of lynparza. Vomiting fatigue upset stomach this includes possible diarrhea constipation and abdominal pain various bone marrow related side. Tell your doctor if you have any new or worsening symptoms of lung problems including shortness of breath fever cough or wheezing.

Drugs that inhibit parp1 cause multiple double strand breaks to form in this way and in tumours with brca1 brca2 or palb2 mutations these double strand breaks cannot be efficiently repaired leading to the death of the cells. Pneumonitis may lead to death. Parp inhibitors cause fewer and less serious side effects than some other cancer treatments. The most common side effects of parp inhibitors are.

The common side effects for all parp inhibitors can include. Managing side effects from parp inhibitors introduction. This additional data was presented at the 2017 san antonio breast cancer symposium and demonstrated that the parp inhibitor is well tolerated by patients and fewer side effects occur compared to chemotherapy poster sessionp5 21 12. Your doctor may temporarily or completely stop treatment if you develop pneumonitis.

As opposed to other toxicities wherein grade 3 and 4 are seen as more. Your doctor may do a chest x ray if you have any of these symptoms. Fast heartbeat hives itching skin rash irritation joint stiffness or swelling redness of the skin swelling of the eyelids face lips hands or feet troubled swallowing. Acid or sour stomach.

Common side effects of parp inhibitors include. Inhibitors of one enzyme parp 1 are being studied in the treatment of breast cancer. Bloody or cloudy urine. Feeling or being sick tiredness diarrhoea indigestion and taste changes headaches and dizziness changes to the way your liver and.

An increased risk of infection bleeding problems tiredness and breathlessness due to a drop in the number of blood.